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NCBI Web Resources:
Global Query.
Query all NCBI Entrez databases in one step.
3D Domains.
3-dimensional views of protein domains and structures.
BLAST.
Compare your sequence to D. discoideum- or other protozoa-specific sequences.
Entrez Gene. Focal point for genes and associated information.
e-PCR. Check your sequence for STSs and view in a genomic context.
GeneRIF. Provides a simple mechanism for scientists to enrich the functional annotation of genes in Entrez Gene.
GEO. Gene Expression Omnibus, a public repository for expression data.
Genome Project. Complete and in-progress large-scale sequencing, assembly, annotation and mapping projects.
Map Viewer. Interactive viewer for genome maps, sequence, and genes.
PubMed Central. Digital archive of full text and content from life sciences journals.
Structure:
Entrez's macromolecular 3D structure database.
Taxonomy. Taxonomy Browser hosts summaries of sequence resources and external links through NCBI's LinkOut.
UniGene. Organization of transcribed sequences into gene-based clusters.
UniSTS. A non-redundant collection of STSs with links to maps and sequence.
Dictyostelium discoideum has been integrated into the Reference Sequence (RefSeq) collection, which aims to provide a comprehensive, non-redundant set of sequences for major research organisms. Based on sequence and annotation provided by the Dictyostelium discoideum Sequencing Consortium and dictyBase, the whole chromosome and annotated mRNA/protein sequences are available as RefSeq records and as individual gene records in the Entrez Gene database.
FTP Sites:
Gene
RefSeq
UniGene
UniSTS
WGS (AAFI)
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Welcome to the Dictyostelium Genome Resources guide. This gateway page will provide one-click links to Dictyostelium-related resources at NCBI and pathways out to additional resources available to the research community. We encourage your suggestions.
© Copyright, Mark Grimson and Larry Blanton, Electron Microscopy Laboratory,
Department of Biological Sciences, Texas Tech University
The social amoeba Dictyostelium discoideum is a useful model organism for biomedical studies because it is easy to grow and has a rapid doubling time, allowing frequent harvesting for study. In addition, its having both single cell and multicellular life stages offers an excellent system for research in developmental and cell biology. The simplicity of its life cycle facilitates mutant selection, where the distinct growth and development stages are easily switched using nutrient variation.
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Latest news...
WGS Project Update: The annotation on version 2 of the Dictyostelium discoideum whole genome shotgun (WGS) project (AAFI00000000) has been updated. The WGS project currently reflects the sequence and annotation that was represented in dictyBase on December 18, 2007. The genomic sequence and annotation, including manually curated genes and gene predictions, are available for display in the dictyBase Genome Browser. View information on the genome sequencing project, and on other genome-related projects, in the Entrez Genome Project Database.
Upcoming Meetings:
International Dictyostelium Conference
Tsukuba-shi, Japan
September 16-20, 2008
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Genomic Biology 
The
Dictyostelium discoideum AX4 genome assembly and annotation (build 2.1) is available in Map Viewer. Take a moment to BLAST your favorite gene sequence against the genome and explore the maps available for viewing.
HIGHLIGHTED RESOURCE: dictyBase is a genome database for Dictyostelium discoideum that acts as a portal for informational resources and offers access to experimental tools available to the Dictyostelium research community.